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Sevelamer is most commonly used in patients with chronic kidney failure, and in particular is used for patients being treated with dialysis. It is often referred to as a phosphate binder. It is a medication that helps to decrease the concentration of phosphate in the blood. It is used to treat patients with hyperphosphatemia, which is a condition marked by high serum phosphate levels. People with chronic kidney failure represent the largest group of patients that have problems with high phosphorus levels in their bodies, since the kidneys are the organs of the body that excrete phosphorus.