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The main health benefit of peonies is their ability to help heal inflammation, according to traditional Chinese medicine. One particular species, paeonia lactiflora, has been used in Chinese medicine to treat rheumatoid arthritis, systemic lupus erythematosus, hepatitis, dysmenorrhea, muscle cramping, spasms and fever. There is a certain amount of science to back this up. Recent research looking at the anti-inflammatory effects of paeonia lactiflora found that it inhibits the production of prostaglandin E2, which induces fever, and leukotriene B4, which promotes insulin resistance. These flowers also help cells communicate by suppressing the increase of intracellular calcium ion concentration. Very clever, indeed.