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About this item ESTROGEN METABOLISM. Research shows diindolylmethane increases the level of “favorable” estrogens (2-hydroxyestrogen) while reducing the level of “less favorable” estrogens (16-hydroxyestrogen).* ENHANCED ABSORPTION. The bioavailability of DIM-plus is superior to regular diindolylmethane and its unstable precursor, indole-3- carbinol (I3C.) With DIM-Plus, you are assured a stabilized and consistent dose of diindolylmethane. DIM-PLUS DIFFERENCE. Contains Indolplex BR-DIM Complex, an enhanced bioavailability delivery system for diindolylmethane, a phytonutrient found in cruciferous vegetables including broccoli, Brussels sprouts, cabbage, cauliflower, and kale. GLUTEN FREE AND VEGETARIAN. No sugar, salt, wheat, yeast, dairy products, artificial flavors, or preservatives.