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The giving of 750 mg/kg BB mangosteen skin water fraction is able to lower an average blood sugar level of 51.47%. Nur Faride Titin Research from the Faculty of Pharmaceuticals, Jember University, East java. Propolis is also able to lower blood sugar levels by controlling the acidity of the body's metabolism. It uncovered in Muhaimin Rifai and Nashi Wldo research from Brawijaya University Biology Department, Unfortunate. They minimize propolis effects on rat blood sugar levels by providing peptides that block insulin receptors. The periset smoothly provides propolis with a dose of 100 mg and 200 mg per kg body weight. The result is that the return cell is able to absorb sugar despite the performance of insulin receptors blocked by peptides. Khoriyoh shoulder research results from the Faculty of the Pharmacy of the Muhamadiyah Surakarta University, showing the giving of number leaf extract as much as 0,500 g per kg effectively lowers blood sugar levels. Mouse blood sugar levels are reduced 188.2 mg / dl in 7 days. Hair seed dried powder brew consumption can lower blood sugar levels. Research of Secretion, Zakir Latif, and Andriani Load Secilia from the Faculty of Pharmaceutical, Pancasila University, South Jakarta.